We are a group of computational, systems, and evolutionary biologists broadly interested in molecular evolution, population genetics, and the dynamics and evolution of gene regulatory networks. Our approach is both theoretical and experimental and we try to tackle the big questions in these fields by building on the latest advances in computer science and systems biology.
LATEST LAB NEWS
|13 Feb. 2019||Tahmid's new clustering method is out in bioinformatics. Software is here|
|21 Dec. 2018||Check out Ian's calcium bursts, now published in G3|
|6 Sept. 2018||Congratulations to Purnima for successfully defending her PhD thesis!|
|4 Jul. 2018||Check out our latest paper in BMC Systems Biology|
|9 Apr. 2018||Congratulations to Clarissa for winning the award for best poster|
|5 Apr. 2018||Alex's paper on a systematic study of protein localization patterns using microscopy images is published in eLife!|
CRZ1 Pulse - From Ian's research project
|Mehdi TF, Singh G, Mitchell JA, Moses AM. Variational Infinite Heterogeneous Mixture Model for Semi-supervised Clustering of Heart Enhancers. Bioinformatics 2019 Feb 7
Bioinformatics link PDF Mirror PubMed Abstract Article
|Hsu IS, Strome B, Plotnikov S, Moses AM. A Noisy Analog-to-Digital Converter Connects Cytosolic Calcium Bursts to Transcription Factor Nuclear Localization Pulses in Yeast. G3 2019 Feb 7;9(2):561-570.
G3 link PDF Mirror PubMed Abstract Article
|Lu AX, Handfield LF, Moses AM. Extracting and Integrating Protein Localization Changes from Multiple Image Screens of Yeast Cells. Bio-protocol Vol 8, Iss 18, Sep 20, 2018.
Bio-protocol link PDF Mirror