We are a group of computational, systems, and evolutionary biologists broadly interested in molecular evolution, population genetics, and the dynamics and evolution of gene regulatory networks. Our approach is both theoretical and experimental and we try to tackle the big questions in these fields by building on the latest advances in computer science and systems biology.
LATEST LAB NEWS
| Dec 2022 | Congratulations to Dr. Nirvana for defending her PhD! |
| Sept 2022 | Congratulations to Aqsa for finishing her MSc! |
| June 2022 | Wow: contrastive learning using evolution as the training signal. Check out Alex's paper. |
| May 2022 | Wishing best of luck to Iva who is starting her group in Graz |
CRZ1 Pulse - From Ian's research project
RECENT PUBLICATIONS
| Duncan AG, Mitchell JA, Moses AM. Improving the performance of supervised deep learning for regulatory genomics using phylogenetic augmentation.Bioinformatics. Published online April 8, 2024. Bioinformatics Link PubMed Abstract Article Deep Learning Phylogenetics Data Augmentation |
| Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME. Developmental dynamics of RNA translation in the human brain. Nat Neurosci. Oct;25(10):1353-1365. Nature Neuroscience Link PDF Mirror PubMed Abstract Article Proteomics Intrinsically Disordered Regions Proteomics Brain |
| Nursimulu N, Moses AM, Parkinson J. Architect: A tool for aiding the reconstruction of high-quality metabolic models through improved enzyme annotation. PLoS Comput Biol. Sep 8;18(9) PLoS Comp. Bio. Link PDF Mirror PubMed Abstract Article Proteomics Metabolic Networks Computational Modelling Bioinformatics |
CONTACT US
The Moses Lab is affiliated with the departments of Cell and Systems Biology, Computer Science, and Ecology and Evolutionary Biology at the University of Toronto. Our lab is in the Ramsay-Wright Labs (25 Harbord St.), located on the southwest side of the St. George Campus. To contact Alan or other lab members, please visit the People page.