Alan Moses

Computational Biology Laboratory

Computational Biology Laboratory

Computational Biology Laboratory

Evolution & Dynamics
of Regulatory Networks
Molecular Evolution
Of Disordered Regions
Genomics & Proteomics
previous arrow
next arrow

Moseslab website

We are a group of computational, systems, and evolutionary biologists broadly interested in molecular evolution, population genetics, and the dynamics and evolution of gene regulatory networks. Our approach is both theoretical and experimental and we try to tackle the big questions in these fields by building on the latest advances in computer science and systems biology.



Dec 2022Congratulations to Dr. Nirvana for defending her PhD!
Sept 2022Congratulations to Aqsa for finishing her MSc!
June 2022Wow: contrastive learning using evolution as the training signal. Check out Alex's paper.
May 2022Wishing best of luck to Iva who is starting her group in Graz

CRZ1 Pulse - From Ian's research project


Hua SBZ, Lu AX, Moses AM. CytoImageNet: A large-scale pretraining dataset for bioimage transfer learning Learning Meaningful Representations of Life (LMRL 2021)
arxiv Link PDF Mirror Article
Deep learning Image Analysis Microscopy Screens
Hsu IS, Strome B, Lash E, Robbins N, Cowen LE, Moses AM. A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling PLoS Genet. 2021 Sep 10; 17(9):e1009629
PLoS Genetics Link PDF Mirror PubMed Abstract Article
Regulatory networks Intrinsically Disordered Regions Time lapse microscopy Cell signalingMolecular evolution
Hsu IS Quantitative Experimental and Mathematical Approaches to Extract Information about Transcription Factor Pulsing University of Toronto 2021 Thesis Link PhD thesis
Computational modeling Regulatory networks Time lapse microscopyCell signaling


The Moses Lab is affiliated with the departments of Cell and Systems Biology, Computer Science, and Ecology and Evolutionary Biology at the University of Toronto. Our lab is in the Ramsay-Wright Labs (25 Harbord St.), located on the southwest side of the St. George Campus. To contact Alan or other lab members, please visit the People page.