We have recently been working on classifying disordered regions for different functions and phenotypes using evolutionary signatures (and signatures comprised of “bulk” feature calculations from disordered sequences). The code and data related to this project currently lives at: https://github.com/taraneh-z/BADR! Check it out and let us know what you think. Hopefully …
If anyone is interested in the raw z-scores underlying Figure 3 from our latest pre-print, you can find them here. You can open the .cdt file as you would any spreadsheet, or import it into TreeView to explore the clusters. UPDATE: The paper is now accepted for publication at eLife, …
With just a few weeks left until my return to Toronto, I’m finally getting around to writing a post about my trip abroad! For readers who are not aware, I’ve spent the last couple of months on a visiting fellowship at the Max Planck Institute for Molecular Cell Biology and …
I’ve been a fan of blogs ever since I became aware of their existence. This must have been sometime around 2002, when I started my first blog on my parents’ AOL trial dial-up connection. I’m not entirely sure why I needed a blog back then, but it ended up being …
I thought it’d be nice to write a summary of my experience at SMBE before returning from Vienna. I’m sitting in the central train station here, fresh off a 12-hour train journey from Berlin. My flight back to Toronto is not for another few hours, and I finally have a …
I’m sure some of you have heard about the millions of golden jellyfish (genus Mastigias) that inhabit landlocked marine lakes in Palau. I only heard about them a couple of days ago, and I think they’re really cool! The different subspecies of golden jellyfish were effectively isolated from their ancestor (the …
It’s the end of day 4, and though we did not venture out for another round at El Hamburger, we’ve still managed to take a lot in. On my left, Alex is in bed with a can of light Puerto Rican beer. On his left lays a sleepy Gavin. One …
Day 3 was a blast. Possibly the most interesting talk came from Michael Desai showing that evolution is not as simple as sequential fixation. Large scale approaches to directly study the evolution of populations were presented, as well as several more outstanding questions that are likely to be answered within …
Day 2 in Puerto Rico. Lots of exciting talks today! Some highlights: – Fernando Racimo from UC Berkeley asking “how far in the past can we detect positive selection on the human genome?” by comparing fixed differences between humans and Neanderthals. Started out by demonstrating that there is significantly lowered …
