Journal club pre-print “Molecular evolution across developmental time reveals rapid divergence in early embryogenesis” by Cutter, A. D., et al
In this pre-print, the authors characterized the transcriptome of C. elegans at 30 timepoints during development. They used fPCA to cluster 14 co-expression modules from 19,711 genes and then fitted a cubic function to the expression profile of each module. The authors then conducted hierarchical clustering on the parameter values …