Yeast isn’t traditionally used as a model for neurodegeneration, but…

From SGD’s New & Noteworthy blog:

[…]of course yeast can’t get the traditional sort of Parkinson’s disease …it doesn’t have a brain.  But it shares enough biology with us that when it expresses a mutant version of α-synuclein (α-syn) that is known to greatly increase a person’s risk for developing Parkinson’s disease, the yeast cell shows many of the same phenotypes as a diseased neuron.  The yeast acts as a stand-in for the neuron.

 

Read the full post here and the paper here

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