If anyone is interested in the raw z-scores underlying Figure 3 from our latest pre-print, you can find them here. You can open the .cdt file as you would any spreadsheet, or import it into TreeView to explore the clusters.
I recently had the opportunity to present some of the super-exciting research progress we are making on image analysis and intrinsically disordered regions. I am making slides available here in case anyone wants to have a closer look.
In this pre-print, the authors characterized the transcriptome of C. elegans at 30 timepoints during development. They used fPCA to cluster 14 co-expression modules from 19,711 genes and then fitted a cubic function to the expression profile of each module. The authors then conducted hierarchical clustering on the parameter values …
Shadi brought us a pie. I proposed to draw a circle with a diameter of 2R and have uniformly random knife cuts on the pie to estimate π with Monte Carlo method. My proposal was rejected.
In our recent journal club, we discussed the pre-print, “Mitigating Data Scarcity in Protein Binding Prediction using Meta-Learning”. Here, Luo et al. apply the recent trend of meta-learning to predicting phosphorylation sites for a poorly characterized kinase family. Meta-learning algorithms aim to discover models that generalize to new predictions with …
I recently attended the ISMB (Intelligent Systems for Molecular Biology) conference in Chicago. This conference is one of the biggest bioinformatics conferences, with scientists from different corners of the world studying a whole range of organisms, systems, models…In fact, the ISMB conference seems to be typically split up into different …
(Sunrise on top of Mt. Fuji) This is the first time I attended a conference of this size, and I expected myself to explore the various topics currently studied in the molecular biology of evolution. One variation among different symposia is the definition of evolution at which the researchers are …
As we have done for the last few years, the lab decided to organize a retreat this year to take some time to think about the big picture: where we are and where we are going. However, this year being the 10th anniversary of the lab, we decided to follow …
As part of our lab’s 10th anniversary celebration this year, I’m proud to unveil our new logo. It has been nearly a year in the making, so thanks to everyone who contributed ideas, feedback and criticism. In the end, we all owe thanks to Ian for the design vision and …
